1995-2010: Over 15 years of MS, I've accumulated 50 "silent" lesions: ones that didn't result in a flare-up. That's 3.33 lesions a year. Only two of the 50 were noisy enough to break though my oblivion, so I've only been in the hospital twice. That's one active lesion every 7.5 years. That is well over the average of one every three years.
(I sound smug, don't I? Hush. You'd be pleased with yourself too. It's a stupid brain, but at least it's discreet. Evidently that's where all my discretion is hiding.)
2011-2013: So, I started 2010 with my fifty vewy-vewy-qwiet lesions. How many do I have now?: Fifty! No new lesions in 2011 or 2012.
The neurologist let me know. We did the seated happy dance together. "The drugs work!"
So, holding pat at fifty.
Then again, it is possible that lesions level out when your estrogen dries up, given that they surmise hormones and MS might be linked. Or, maybe lesions top out at fifty. Maybe they stop counting at fifty. Or maybe it's like the rings on a tree: you earn one for every year you've been alive. No, then that means I'd have been dead the last two years because NO NEW LESIONS.